Certain patients with severe asthma as well as year-round allergies (to dust mites, animal dander, or cockroach) may benefit from Xolair® (omalizumab; Merck) every 2-4 weeks, approved for children 6 and up and adults. It is also used every 4 weeks to treat chronic idiopathic urticaria (hives) in children 12 and up and adults. Nucala® (mepolizumab; GlaxoSmithKline) is a monthly injectable medication that works by reducing the number of eosinophils (allergy cells) in asthma patients 12 and older. These are injections given in the allergist's office due to risk of allergic reaction, with mandatory wait period after administration. Patients often experience dramatic reduction in severity of symptoms while on treatment. Need for continued therapy is evaluated at periodic follow-up intervals.
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