Certain patients with frequent infections or need for hospitalizations, or long-term, high-dose antibiotic therapy to control infections, or recurrent diarrhea, or near-constant sinusitis, or growth of atypical bacteria or fungus or virus warrant further investigation into the status of their immune system to determine whether it is functioning appropriately. Patients may have a family history of immunodeficiency disorders, while for others, they are the only family member affected. Patients with primary immunodeficiency diseases can have a higher risk of developing autoimmune disorders or even cancers, so proper diagnosis and management with an Allergist/Immunologist in coordination with other appropriate specialists including Rheumatology, Pulmonary, Infectious Disease, ENT, Oncology, Hematology, and Geneticists can be extremely helpful in managing the health of the entire patient.
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